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Activation of cannabinoid receptor 2 reduces inflammation in acute...
“The endocannabinoid system has been shown to mediate beneficial effects on gastrointestinal inflammation via cannabinoid receptors 1 (CB(1)) and 2 (CB(2)). These receptors have also been reported to...
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Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces...
“Acute pancreatitis is an inflammatory disease, which has several causes and symptoms and requires immediate medical attention. The cannabinoid receptor type 2 (CB2R) is a G protein-coupled receptor...
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Cannabinoid HU210 Protects Isolated Rat Stomach against Impairment Caused by...
“Acute pancreatitis (AP), especially severe AP, is a potentially lethal inflammatory disease of pancreas which often leads to extra-pancreatic complications, even multiple systemic organ dysfunctions....
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Cannabinoid agonist WIN55,212 in vitro inhibits interleukin-6 (IL-6) and...
“Cannabinoids (CBs) evoke their effects by activating the cannabinoid receptor subtypes CB1-r and CB2-r and exert anti-inflammatory effects altering chemokine and cytokine expression. Various...
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Cannabinoid receptor-1 blockade attenuates acute pancreatitis in obesity by...
“Obesity is a risk factor for increased severity of acute pancreatitis. Adipocytes produce adiponectin, an anti-inflammatory molecule that is paradoxically decreased in the setting of obesity. We have...
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The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats...
“It has recently been recognized that anandamide (arachidonylethanolamide), which is an endogeneous-cannabinoid (endocannabinoid), mediates septic shock. Cannabinoid means a mind-active material in...
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Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+...
“We recently reported that a CB2R agonist, GW405833 (GW), reduced both the ACh-induced Ca2+ oscillations and the L-arginine-induced Ca2+ signal enhancement in mouse pancreatic acinar cells, suggesting...
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Reduced Risk of Alcohol-Induced Pancreatitis With Cannabis Use.
“Pancreatitis is an increasingly common clinical condition that causes significant morbidity and mortality. Cannabis use causes conflicting effects on pancreatitis development. We conducted a larger...
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The Impact of Cannabis Consumption on Mortality, Morbidity, and Cost in Acute...
“The aim of this study was to identify the prevalence of cannabis use among all patients admitted with acute pancreatitis (AP) in the United States and to investigate the impact of cannabis use on AP...
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Cannabidiol Mitigates Lipopolysaccharide-Induced Pancreatic Pathology: A...
“Background: Lipopolysaccharides (LPSs) are a component of certain types of bacteria and can induce an inflammatory response in the body, including in the pancreas. Cannabidiol (CBD), a...
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